Gene Networks of Fully Connected Triads with Complete Auto-Activation Enable Multistability and Stepwise Stochastic Transitions

Fully-connected triads (FCTs), such as the Oct4-Sox2-Nanog triad, have been implicated as recurring transcriptional motifs embedded within the regulatory networks that specify and maintain cellular states. To explore the possible connections between FCT topologies and cell fate determinations, we em...

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Detalles Bibliográficos
Autores principales: Faucon, Philippe C., Pardee, Keith, Kumar, Roshan M., Li, Hu, Loh, Yuin-Han, Wang, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109943/
https://www.ncbi.nlm.nih.gov/pubmed/25057990
http://dx.doi.org/10.1371/journal.pone.0102873

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109943/
https://www.ncbi.nlm.nih.gov/pubmed/25057990
http://dx.doi.org/10.1371/journal.pone.0102873

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