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The Cellular Prion Protein Negatively Regulates Phagocytosis and Cytokine Expression in Murine Bone Marrow-Derived Macrophages

The cellular prion protein (PrP(C)) is a glycosylphosphatidylinositol (GPI)-anchored glycoprotein on the cell surface. Previous studies have demonstrated contradictory roles for PrP(C) in connection with the phagocytic ability of macrophages. In the present work, we investigated the function of PrP(...

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Detalles Bibliográficos
Autores principales: Wang, Min, Zhao, Deming, Yang, Yang, Liu, Jin, Wang, Jin, Yin, Xiaomin, Yang, Lifeng, Zhou, Xiangmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109954/
https://www.ncbi.nlm.nih.gov/pubmed/25058617
http://dx.doi.org/10.1371/journal.pone.0102785