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The Cellular Prion Protein Negatively Regulates Phagocytosis and Cytokine Expression in Murine Bone Marrow-Derived Macrophages
The cellular prion protein (PrP(C)) is a glycosylphosphatidylinositol (GPI)-anchored glycoprotein on the cell surface. Previous studies have demonstrated contradictory roles for PrP(C) in connection with the phagocytic ability of macrophages. In the present work, we investigated the function of PrP(...
Autores principales: | Wang, Min, Zhao, Deming, Yang, Yang, Liu, Jin, Wang, Jin, Yin, Xiaomin, Yang, Lifeng, Zhou, Xiangmei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109954/ https://www.ncbi.nlm.nih.gov/pubmed/25058617 http://dx.doi.org/10.1371/journal.pone.0102785 |
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