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Serotonin transporter genotype modulates HPA axis output during stress: effect of stress, dexamethasone test and ACTH challenge

BACKGROUND: Studies show that the hypothalamic–pituitary–adrenal (HPA) axis is dysregulated in depression. Some studies suggest that variation in the serotonin transporter genotype (hereafter 5HTT) modulates both risk for depression and psychopathological HPA axis responsiveness. Rhesus monkeys are...

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Detalles Bibliográficos
Autores principales: Sorenson, Andrea N., Sullivan, Erin C., Mendoza, Sally P., Capitanio, John P., Higley, J. Dee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109987/
https://www.ncbi.nlm.nih.gov/pubmed/25068032
http://dx.doi.org/10.3402/tdp.v1i0.21130