Screening of ROS1 Rearrangements in Lung Adenocarcinoma by Immunohistochemistry and Comparison with ALK Rearrangements

ROS1 rearrangement is a predictive biomarker for response to the tyrosine kinase inhibitor, crizotinib. We investigated the usefulness of ROS1 immunohistochemistry (IHC) for the detection of patients who harbor ROS1 rearrangements in two separate cohorts. We also compared ROS1 IHC with ALK IHC in te...

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Detalles Bibliográficos
Autores principales: Cha, Yoon Jin, Lee, Jae Seok, Kim, Hye Ryun, Lim, Sun Min, Cho, Byoung Chul, Lee, Chang Young, Shim, Hyo Sup
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109990/
https://www.ncbi.nlm.nih.gov/pubmed/25058391
http://dx.doi.org/10.1371/journal.pone.0103333

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109990/
https://www.ncbi.nlm.nih.gov/pubmed/25058391
http://dx.doi.org/10.1371/journal.pone.0103333

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