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Roles of PI3K/Akt and c-Jun Signaling Pathways in Human Papillomavirus Type 16 Oncoprotein-Induced HIF-1α, VEGF, and IL-8 Expression and In Vitro Angiogenesis in Non-Small Cell Lung Cancer Cells

BACKGROUND AND OBJECTIVES: Human papillomavirus (HPV)-16 infection may be related to non-smoking associated lung cancer. Our previous studies have found that HPV-16 oncoproteins promoted angiogenesis via enhancing hypoxia-inducible factor-1α (HIF-1α), vascular endothelial growth factor (VEGF), and i...

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Detalles Bibliográficos
Autores principales: Zhang, Erying, Feng, Xiaowei, Liu, Fei, Zhang, Peihua, Liang, Jie, Tang, Xudong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110025/
https://www.ncbi.nlm.nih.gov/pubmed/25058399
http://dx.doi.org/10.1371/journal.pone.0103440