The CD27L and CTP1L Endolysins Targeting Clostridia Contain a Built-in Trigger and Release Factor

The bacteriophage ΦCD27 is capable of lysing Clostridium difficile, a pathogenic bacterium that is a major cause for nosocomial infection. A recombinant CD27L endolysin lyses C. difficile in vitro, and represents a promising alternative as a bactericide. To better understand the lysis mechanism, we...

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Detalles Bibliográficos
Autores principales: Dunne, Matthew, Mertens, Haydyn D. T., Garefalaki, Vasiliki, Jeffries, Cy M., Thompson, Andrew, Lemke, Edward A., Svergun, Dmitri I., Mayer, Melinda J., Narbad, Arjan, Meijers, Rob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110038/
https://www.ncbi.nlm.nih.gov/pubmed/25058163
http://dx.doi.org/10.1371/journal.ppat.1004228

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110038/
https://www.ncbi.nlm.nih.gov/pubmed/25058163
http://dx.doi.org/10.1371/journal.ppat.1004228

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