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Visfatin is involved in TNFα-mediated insulin resistance via an NAD(+)/Sirt1/PTP1B pathway in 3T3-L1 adipocytes

Tumor necrosis factor α (TNFα) is a well-known mediator of inflammation in the context of obesity in adipose tissue. Its action appears to be directly linked to perturbations of the insulin pathway, leading to the development of insulin resistance. Visfatin has been suspected to be linked to insulin...

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Detalles Bibliográficos
Autores principales: Gouranton, Erwan, Romier, Béatrice, Marcotorchino, Julie, Tourniaire, Franck, Astier, Julien, Peiretti, Franck, Landrier, Jean-François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110094/
https://www.ncbi.nlm.nih.gov/pubmed/25068084
http://dx.doi.org/10.4161/adip.28729