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Visfatin is involved in TNFα-mediated insulin resistance via an NAD(+)/Sirt1/PTP1B pathway in 3T3-L1 adipocytes
Tumor necrosis factor α (TNFα) is a well-known mediator of inflammation in the context of obesity in adipose tissue. Its action appears to be directly linked to perturbations of the insulin pathway, leading to the development of insulin resistance. Visfatin has been suspected to be linked to insulin...
Autores principales: | Gouranton, Erwan, Romier, Béatrice, Marcotorchino, Julie, Tourniaire, Franck, Astier, Julien, Peiretti, Franck, Landrier, Jean-François |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110094/ https://www.ncbi.nlm.nih.gov/pubmed/25068084 http://dx.doi.org/10.4161/adip.28729 |
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