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Characterization of Cre recombinase models for the study of adipose tissue

The study of adipose tissue in vivo has been significantly advanced through the use of genetic mouse models. While the aP2-Cre(BI) and aP2-Cre(Salk) lines have been widely used to target adipose tissue, the specificity of these lines for adipocytes has recently been questioned. Here we characterize...

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Detalles Bibliográficos
Autores principales: Jeffery, Elise, Berry, Ryan, Church, Christopher D, Yu, Songtao, Shook, Brett A, Horsley, Valerie, Rosen, Evan D, Rodeheffer, Matthew S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110097/
https://www.ncbi.nlm.nih.gov/pubmed/25068087
http://dx.doi.org/10.4161/adip.29674