Reactivation of cocaine reward memory engages the Akt/GSK3/mTOR signaling pathway and can be disrupted by GSK3 inhibition

RATIONAL: Memories return to a labile state following their retrieval and must undergo a process of reconsolidation to be maintained. Thus, disruption of cocaine reward memories by interference with reconsolidation may be therapeutically beneficial in the treatment of cocaine addiction. OBJECTIVE: T...

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Detalles Bibliográficos
Autores principales: Shi, Xiangdang, Miller, Jonathan S., Harper, Lauren J., Poole, Rachel L., Gould, Thomas J., Unterwald, Ellen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110417/
https://www.ncbi.nlm.nih.gov/pubmed/24595501
http://dx.doi.org/10.1007/s00213-014-3491-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110417/
https://www.ncbi.nlm.nih.gov/pubmed/24595501
http://dx.doi.org/10.1007/s00213-014-3491-8

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