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Safety and outcome of treatment of metastatic melanoma using 3-bromopyruvate: a concise literature review and case study

3-Bromopyruvate (3BP) is a new, promising anticancer alkylating agent with several notable functions. In addition to inhibiting key glycolysis enzymes including hexokinase II and lactate dehydrogenase (LDH), 3BP also selectively inhibits mitochondrial oxidative phosphorylation, angiogenesis, and ene...

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Detalles Bibliográficos
Autores principales: El Sayed, Salah Mohamed, Mohamed, Walaa Gamal, Seddik, Minnat-Allah Hassan, Ahmed, Al-Shimaa Ahmed, Mahmoud, Asmaa Gamal, Amer, Wael Hassan, Helmy Nabo, Manal Mohamed, Hamed, Ahmed Roshdi, Ahmed, Nagwa Sayed, Abd-Allah, Ali Abdel-Rahman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sun Yat-sen University Cancer Center 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110469/
https://www.ncbi.nlm.nih.gov/pubmed/24636230
http://dx.doi.org/10.5732/cjc.013.10111