Primate evolution of the recombination regulator PRDM9

The PRDM9 gene encodes a protein with a highly variable tandem-repeat zinc finger (ZF) DNA-binding domain that plays a key role in determining sequence-specific hotspots of meiotic recombination genome-wide. Here we survey the diversity of the PRDM9 ZF domain by sequencing this region in 64 primates...

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Detalles Bibliográficos
Autores principales: Schwartz, Jerrod J., Roach, David J., Thomas, James H., Shendure, Jay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110516/
https://www.ncbi.nlm.nih.gov/pubmed/25001002
http://dx.doi.org/10.1038/ncomms5370

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110516/
https://www.ncbi.nlm.nih.gov/pubmed/25001002
http://dx.doi.org/10.1038/ncomms5370

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