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Preparation and nanoencapsulation of l-asparaginase II in chitosan-tripolyphosphate nanoparticles and in vitro release study

This paper describes the production, purification, and immobilization of l-asparaginase II (ASNase II) in chitosan nanoparticles (CSNPs). ASNase II is an effective antineoplastic agent, used in the acute lymphoblastic leukemia chemotherapy. Cloned ASNase II gene (ansB) in pAED4 plasmid was transform...

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Detalles Bibliográficos
Autores principales: Bahreini, Elham, Aghaiypour, Khosrow, Abbasalipourkabir, Roghayeh, Mokarram, Ali Rezaei, Goodarzi, Mohammad Taghi, Saidijam, Massoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110547/
https://www.ncbi.nlm.nih.gov/pubmed/25114635
http://dx.doi.org/10.1186/1556-276X-9-340