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CD39 is a negative regulator of P2X7-mediated inflammatory cell death in mast cells
BACKGROUND: Mast cells (MCs) are major contributors to an inflammatory milieu. One of the most potent drivers of inflammation is the cytokine IL-1β, which is produced in the cytoplasm in response to danger signals like LPS. Several controlling mechanisms have been reported which limit the release of...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110707/ https://www.ncbi.nlm.nih.gov/pubmed/25184735 http://dx.doi.org/10.1186/s12964-014-0040-3 |