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Structure prediction of polyglutamine disease proteins: comparison of methods
BACKGROUND: The expansion of polyglutamine (poly-Q) repeats in several unrelated proteins is associated with at least ten neurodegenerative diseases. The length of the poly-Q regions plays an important role in the progression of the diseases. The number of glutamines (Q) is inversely related to the...
Autores principales: | Wen, Jingran, Scoles, Daniel R, Facelli, Julio C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110737/ https://www.ncbi.nlm.nih.gov/pubmed/25080018 http://dx.doi.org/10.1186/1471-2105-15-S7-S11 |
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