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Mechanisms for Interferon-α-Induced Depression and Neural Stem Cell Dysfunction

New neurons generated by the neural stem cells (NSCs) in the adult hippocampus play an important role in emotional regulation and respond to the action of antidepressants. Depression is a common and serious side effect of interferon-α (IFN-α), which limits its use as an antiviral and antitumor drug....

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Detalles Bibliográficos
Autores principales: Zheng, Lian-Shun, Hitoshi, Seiji, Kaneko, Naoko, Takao, Keizo, Miyakawa, Tsuyoshi, Tanaka, Yasuhito, Xia, Hongjing, Kalinke, Ulrich, Kudo, Koutaro, Kanba, Shigenobu, Ikenaka, Kazuhiro, Sawamoto, Kazunobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110771/
https://www.ncbi.nlm.nih.gov/pubmed/25068123
http://dx.doi.org/10.1016/j.stemcr.2014.05.015