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Mechanisms for Interferon-α-Induced Depression and Neural Stem Cell Dysfunction
New neurons generated by the neural stem cells (NSCs) in the adult hippocampus play an important role in emotional regulation and respond to the action of antidepressants. Depression is a common and serious side effect of interferon-α (IFN-α), which limits its use as an antiviral and antitumor drug....
Autores principales: | Zheng, Lian-Shun, Hitoshi, Seiji, Kaneko, Naoko, Takao, Keizo, Miyakawa, Tsuyoshi, Tanaka, Yasuhito, Xia, Hongjing, Kalinke, Ulrich, Kudo, Koutaro, Kanba, Shigenobu, Ikenaka, Kazuhiro, Sawamoto, Kazunobu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110771/ https://www.ncbi.nlm.nih.gov/pubmed/25068123 http://dx.doi.org/10.1016/j.stemcr.2014.05.015 |
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