Wilms’ Tumor Blastemal Stem Cells Dedifferentiate to Propagate the Tumor Bulk

An open question remains in cancer stem cell (CSC) biology whether CSCs are by definition at the top of the differentiation hierarchy of the tumor. Wilms’ tumor (WT), composed of blastema and differentiated renal elements resembling the nephrogenic zone of the developing kidney, is a valuable model...

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Detalles Bibliográficos
Autores principales: Shukrun, Rachel, Pode-Shakked, Naomi, Pleniceanu, Oren, Omer, Dorit, Vax, Einav, Peer, Eyal, Pri-Chen, Sara, Jacob, Jasmine, Hu, Qianghua, Harari-Steinberg, Orit, Huff, Vicki, Dekel, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110791/
https://www.ncbi.nlm.nih.gov/pubmed/25068119
http://dx.doi.org/10.1016/j.stemcr.2014.05.013

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