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Sustained ERK Activation Underlies Reprogramming in Regeneration-Competent Salamander Cells and Distinguishes Them from Their Mammalian Counterparts

In regeneration-competent vertebrates, such as salamanders, regeneration depends on the ability of various differentiated adult cell types to undergo natural reprogramming. This ability is rarely observed in regeneration-incompetent species such as mammals, providing an explanation for their poor re...

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Detalles Bibliográficos
Autores principales: Yun, Maximina H., Gates, Phillip B., Brockes, Jeremy P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110794/
https://www.ncbi.nlm.nih.gov/pubmed/25068118
http://dx.doi.org/10.1016/j.stemcr.2014.05.009