Probing SH2-domains using Inhibitor Affinity Purification (IAP)

BACKGROUND: Many human diseases are correlated with the dysregulation of signal transduction processes. One of the most important protein interaction domains in the context of signal transduction is the Src homology 2 (SH2) domain that binds phosphotyrosine residues. Hence, appropriate methods for t...

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Detalles Bibliográficos
Autores principales: Höfener, Michael, Heinzlmeir, Stephanie, Kuster, Bernhard, Sewald, Norbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110944/
https://www.ncbi.nlm.nih.gov/pubmed/25067910
http://dx.doi.org/10.1186/1477-5956-12-41

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110944/
https://www.ncbi.nlm.nih.gov/pubmed/25067910
http://dx.doi.org/10.1186/1477-5956-12-41

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