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Probing SH2-domains using Inhibitor Affinity Purification (IAP)
BACKGROUND: Many human diseases are correlated with the dysregulation of signal transduction processes. One of the most important protein interaction domains in the context of signal transduction is the Src homology 2 (SH2) domain that binds phosphotyrosine residues. Hence, appropriate methods for t...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110944/ https://www.ncbi.nlm.nih.gov/pubmed/25067910 http://dx.doi.org/10.1186/1477-5956-12-41 |