REST and Stress Resistance in Aging and Alzheimer’s Disease

Human neurons are functional over an entire lifetime, yet the mechanisms that preserve function and protect against neurodegeneration during aging are unknown. Here we show that induction of the repressor element 1-silencing transcription/neuron-restrictive silencer factor (REST/NRSF) is a universal...

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Detalles Bibliográficos
Autores principales: Lu, Tao, Aron, Liviu, Zullo, Joseph, Pan, Ying, Kim, Haeyoung, Chen, Yiwen, Yang, Tun-Hsiang, Kim, Hyun-Min, Drake, Derek, Liu, X. Shirley, Bennett, David A., Colaiácovo, Monica P., Yankner, Bruce A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110979/
https://www.ncbi.nlm.nih.gov/pubmed/24670762
http://dx.doi.org/10.1038/nature13163

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110979/
https://www.ncbi.nlm.nih.gov/pubmed/24670762
http://dx.doi.org/10.1038/nature13163

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