Lipidation of the LC3/GABARAP family of autophagy proteins relies upon a membrane curvature-sensing domain in Atg3

The protein biochemistry supporting autophagosome growth on the cup-like isolation membrane is likely different from the biochemistry on the closed and maturing autophagosome. Thus, the highly curved rim of the cup may serve as a functionally-required surface for transiently-associated components of...

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Detalles Bibliográficos
Autores principales: Nath, Sangeeta, Dancourt, Julia, Shteyn, Vladimir, Puente, Gabriella, Fong, Wendy M., Nag, Shanta, Bewersdorf, Joerg, Yamamoto, Ai, Antonny, Bruno, Melia., Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111135/
https://www.ncbi.nlm.nih.gov/pubmed/24747438
http://dx.doi.org/10.1038/ncb2940

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111135/
https://www.ncbi.nlm.nih.gov/pubmed/24747438
http://dx.doi.org/10.1038/ncb2940

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