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Lipidation of the LC3/GABARAP family of autophagy proteins relies upon a membrane curvature-sensing domain in Atg3
The protein biochemistry supporting autophagosome growth on the cup-like isolation membrane is likely different from the biochemistry on the closed and maturing autophagosome. Thus, the highly curved rim of the cup may serve as a functionally-required surface for transiently-associated components of...
Autores principales: | Nath, Sangeeta, Dancourt, Julia, Shteyn, Vladimir, Puente, Gabriella, Fong, Wendy M., Nag, Shanta, Bewersdorf, Joerg, Yamamoto, Ai, Antonny, Bruno, Melia., Thomas J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111135/ https://www.ncbi.nlm.nih.gov/pubmed/24747438 http://dx.doi.org/10.1038/ncb2940 |
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