Independent Origin of Plasmodium falciparum Antifolate Super-Resistance, Uganda, Tanzania, and Ethiopia

Super-resistant Plasmodium falciparum threatens the effectiveness of sulfadoxine–pyrimethamine in intermittent preventive treatment for malaria during pregnancy. It is characterized by the A581G Pfdhps mutation on a background of the double-mutant Pfdhps and the triple-mutant Pfdhfr. Using samples c...

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Detalles Bibliográficos
Autores principales: Alifrangis, Michael, Nag, Sidsel, Schousboe, Mette L., Ishengoma, Deus, Lusingu, John, Pota, Hirva, Kavishe, Reginald A., Pearce, Richard, Ord, Rosalynn, Lynch, Caroline, Dejene, Seyoum, Cox, Jonathan, Rwakimari, John, Minja, Daniel T.R., Lemnge, Martha M., Roper, Cally
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111169/
https://www.ncbi.nlm.nih.gov/pubmed/25061906
http://dx.doi.org/10.3201/eid2008.131897

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111169/
https://www.ncbi.nlm.nih.gov/pubmed/25061906
http://dx.doi.org/10.3201/eid2008.131897

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