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Independent Origin of Plasmodium falciparum Antifolate Super-Resistance, Uganda, Tanzania, and Ethiopia
Super-resistant Plasmodium falciparum threatens the effectiveness of sulfadoxine–pyrimethamine in intermittent preventive treatment for malaria during pregnancy. It is characterized by the A581G Pfdhps mutation on a background of the double-mutant Pfdhps and the triple-mutant Pfdhfr. Using samples c...
Autores principales: | Alifrangis, Michael, Nag, Sidsel, Schousboe, Mette L., Ishengoma, Deus, Lusingu, John, Pota, Hirva, Kavishe, Reginald A., Pearce, Richard, Ord, Rosalynn, Lynch, Caroline, Dejene, Seyoum, Cox, Jonathan, Rwakimari, John, Minja, Daniel T.R., Lemnge, Martha M., Roper, Cally |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Centers for Disease Control and Prevention
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111169/ https://www.ncbi.nlm.nih.gov/pubmed/25061906 http://dx.doi.org/10.3201/eid2008.131897 |
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