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Thermodynamic Mechanism for the Evasion of Antibody Neutralization in Flaviviruses
[Image: see text] Mutations in the epitopes of antigenic proteins can confer viral resistance to antibody-mediated neutralization. However, the fundamental properties that characterize epitope residues and how mutations affect antibody binding to alter virus susceptibility to neutralization remain l...
Autores principales: | Maillard, Rodrigo A., Liu, Tong, Beasley, David W. C., Barrett, Alan D. T., Hilser, Vincent J., Lee, J. Ching |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111217/ https://www.ncbi.nlm.nih.gov/pubmed/24950171 http://dx.doi.org/10.1021/ja503318x |
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