Molecular Docking Simulations Provide Insights in the Substrate Binding Sites and Possible Substrates of the ABCC6 Transporter

The human ATP-binding cassette family C member 6 (ABCC6) gene encodes an ABC transporter protein (ABCC6), primarily expressed in liver and kidney. Mutations in the ABCC6 gene cause pseudoxanthoma elasticum (PXE), an autosomal recessive connective tissue disease characterized by ectopic mineralizatio...

Descripción completa

Detalles Bibliográficos
Autores principales: Hosen, Mohammad Jakir, Zubaer, Abdullah, Thapa, Simrika, Khadka, Bijendra, De Paepe, Anne, Vanakker, Olivier M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111409/
https://www.ncbi.nlm.nih.gov/pubmed/25062064
http://dx.doi.org/10.1371/journal.pone.0102779

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111409/
https://www.ncbi.nlm.nih.gov/pubmed/25062064
http://dx.doi.org/10.1371/journal.pone.0102779

Ejemplares similares