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Molecular Docking Simulations Provide Insights in the Substrate Binding Sites and Possible Substrates of the ABCC6 Transporter
The human ATP-binding cassette family C member 6 (ABCC6) gene encodes an ABC transporter protein (ABCC6), primarily expressed in liver and kidney. Mutations in the ABCC6 gene cause pseudoxanthoma elasticum (PXE), an autosomal recessive connective tissue disease characterized by ectopic mineralizatio...
Autores principales: | Hosen, Mohammad Jakir, Zubaer, Abdullah, Thapa, Simrika, Khadka, Bijendra, De Paepe, Anne, Vanakker, Olivier M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111409/ https://www.ncbi.nlm.nih.gov/pubmed/25062064 http://dx.doi.org/10.1371/journal.pone.0102779 |
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