Thrombin Enhances NGF-Mediated Neurite Extension via Increased and Sustained Activation of p44/42 MAPK and p38 MAPK

Rapid neurite remodeling is fundamental to nervous system development and plasticity. It involves neurite extension that is regulated by NGF through PI3K/AKT, p44/42 MAPK and p38 MAPK. It also involves neurite retraction that is regulated by the serine protease, thrombin. However, the intracellular...

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Detalles Bibliográficos
Autores principales: Mufti, Rania E., Sarker, Krishna, Jin, Yan, Fu, Songbin, Rosales, Jesusa L., Lee, Ki-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111596/
https://www.ncbi.nlm.nih.gov/pubmed/25061982
http://dx.doi.org/10.1371/journal.pone.0103530

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111596/
https://www.ncbi.nlm.nih.gov/pubmed/25061982
http://dx.doi.org/10.1371/journal.pone.0103530

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