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Thrombin Enhances NGF-Mediated Neurite Extension via Increased and Sustained Activation of p44/42 MAPK and p38 MAPK
Rapid neurite remodeling is fundamental to nervous system development and plasticity. It involves neurite extension that is regulated by NGF through PI3K/AKT, p44/42 MAPK and p38 MAPK. It also involves neurite retraction that is regulated by the serine protease, thrombin. However, the intracellular...
Autores principales: | Mufti, Rania E., Sarker, Krishna, Jin, Yan, Fu, Songbin, Rosales, Jesusa L., Lee, Ki-Young |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111596/ https://www.ncbi.nlm.nih.gov/pubmed/25061982 http://dx.doi.org/10.1371/journal.pone.0103530 |
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