Inhibition of Endocannabinoid Metabolism by the Metabolites of Ibuprofen and Flurbiprofen

BACKGROUND: In addition to their effects upon prostaglandin synthesis, the non-steroidal anti-inflammatory drugs ibuprofen and flurbiprofen inhibit the metabolism of the endocannabinoids 2-arachidonoylglycerol (2-AG) and anandamide (AEA) by cyclooxygenase-2 (COX-2) and fatty acid amide hydrolase (FA...

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Detalles Bibliográficos
Autores principales: Karlsson, Jessica, Fowler, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111603/
https://www.ncbi.nlm.nih.gov/pubmed/25061885
http://dx.doi.org/10.1371/journal.pone.0103589

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111603/
https://www.ncbi.nlm.nih.gov/pubmed/25061885
http://dx.doi.org/10.1371/journal.pone.0103589

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