Sulforaphane reverses glucocorticoid-induced apoptosis in osteoblastic cells through regulation of the Nrf2 pathway

Apoptosis of osteoblasts triggered by high-dose glucocorticoids (GCs) has been identified as a major cause of osteoporosis. However, the underlying molecular mechanisms accounting for this action remain elusive, which has impeded the prevention and cure of this side effect. Sulforaphane (SFP) is a n...

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Detalles Bibliográficos
Autores principales: Lin, Hao, Wei, Bo, Li, Guangsheng, Zheng, Jinchang, Sun, Jiecong, Chu, Jiaqi, Zeng, Rong, Niu, Yanru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111650/
https://www.ncbi.nlm.nih.gov/pubmed/25071366
http://dx.doi.org/10.2147/DDDT.S65410

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111650/
https://www.ncbi.nlm.nih.gov/pubmed/25071366
http://dx.doi.org/10.2147/DDDT.S65410

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