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Sulforaphane reverses glucocorticoid-induced apoptosis in osteoblastic cells through regulation of the Nrf2 pathway
Apoptosis of osteoblasts triggered by high-dose glucocorticoids (GCs) has been identified as a major cause of osteoporosis. However, the underlying molecular mechanisms accounting for this action remain elusive, which has impeded the prevention and cure of this side effect. Sulforaphane (SFP) is a n...
Autores principales: | Lin, Hao, Wei, Bo, Li, Guangsheng, Zheng, Jinchang, Sun, Jiecong, Chu, Jiaqi, Zeng, Rong, Niu, Yanru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111650/ https://www.ncbi.nlm.nih.gov/pubmed/25071366 http://dx.doi.org/10.2147/DDDT.S65410 |
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