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BCL10 regulates RNF8/RNF168-mediated ubiquitination in the DNA damage response

Timely and proper cellular response to DNA damage is essential for maintenance of genome stability and integrity. B-cell lymphoma/leukemia 10 (BCL10) facilitates ubiquitination of NEMO in the cytosol, activating NFκB signaling. Translocation and/or point mutations of BCL10 associate with mucosa-asso...

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Detalles Bibliográficos
Autores principales: Zhao, Hongchang, Zhu, Min, Dou, Gelin, Zhao, Hongli, Zhu, Bingtao, Li, Jing, Liao, Ji, Xu, Xingzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111724/
https://www.ncbi.nlm.nih.gov/pubmed/24732096
http://dx.doi.org/10.4161/cc.28707