Transamidase subunit GAA1/GPAA1 is a M28 family metallo-peptide-synthetase that catalyzes the peptide bond formation between the substrate protein’s omega-site and the GPI lipid anchor’s phosphoethanolamine

The transamidase subunit GAA1/GPAA1 is predicted to be the enzyme that catalyzes the attachment of the glycosylphosphatidyl (GPI) lipid anchor to the carbonyl intermediate of the substrate protein at the ω-site. Its ~300-amino acid residue lumenal domain is a M28 family metallo-peptide-synthetase wi...

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Detalles Bibliográficos
Autores principales: Eisenhaber, Birgit, Eisenhaber, Stephan, Kwang, Toh Yew, Grüber, Gerhard, Eisenhaber, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111754/
https://www.ncbi.nlm.nih.gov/pubmed/24743167
http://dx.doi.org/10.4161/cc.28761

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111754/
https://www.ncbi.nlm.nih.gov/pubmed/24743167
http://dx.doi.org/10.4161/cc.28761

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