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Host genetics and immune control of HIV-1 infection: Fine mapping for the extended human MHC region in an African cohort

Multiple MHC loci encoding human leukocyte antigens (HLA) have allelic variants unequivocally associated with differential immune control of HIV-1 infection. Fine mapping based on single nucleotide polymorphisms (SNPs) in the extended MHC (xMHC) region is expected to reveal causal or novel factors a...

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Detalles Bibliográficos
Autores principales: Prentice, Heather A., Pajewski, Nicholas M., He, Dongning, Zhang, Kui, Brown, Elizabeth E., Kilembe, William, Allen, Susan, Hunter, Eric, Kaslow, Richard A., Tang, Jianming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111776/
https://www.ncbi.nlm.nih.gov/pubmed/24784026
http://dx.doi.org/10.1038/gene.2014.16