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Anti-onchocerca Metabolites from Cyperus articulatus: Isolation, In Vitro Activity and In Silico ‘Drug-Likeness’

The aims of this investigation were to isolate active ingredients from the roots/rhizomes of Cyperus articulatus used as herbal medicine in Cameroon for the treatment of human onchocerciasis and to assess the efficacy of the metabolites on the Onchocerca worm. The antifilarial activity was evaluated...

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Detalles Bibliográficos
Autores principales: Metuge, Jonathan Alunge, Babiaka, Smith B., Mbah, James A., Ntie-Kang, Fidele, Ayimele, Godfred A., Cho-Ngwa, Fidelis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111868/
https://www.ncbi.nlm.nih.gov/pubmed/25089243
http://dx.doi.org/10.1007/s13659-014-0023-5