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Molecular Docking of Bacosides with Tryptophan Hydroxylase: A Model to Understand the Bacosides Mechanism

Tryptophan hydroxylase (TPH) catalyses l-tryptophan into 5-hydroxy-l-tryptophan, which is the first and rate-limiting step of serotonin (5-HT) biosynthesis. Earlier, we found that TPH2 up-regulated in the hippocampus of postnatal rats after the oral treatment of Bacopa monniera leaf extract containi...

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Detalles Bibliográficos
Autores principales: Rajathei, David Mary, Preethi, Jayakumar, Singh, Hemant K., Rajan, Koilmani Emmanuvel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111882/
https://www.ncbi.nlm.nih.gov/pubmed/25089244
http://dx.doi.org/10.1007/s13659-014-0031-5