Complexing Aβ Prevents the Cellular Anomalies Induced by the Peptide Alone

Retention of intracellular secreted APP (isAPP) can be provoked by the neurotoxic peptide Aβ. The latter decreases in the cerebrospinal fluid of Alzheimer’s disease (AD) patients, as a consequence of its cerebral accumulation and deposition into senile plaques. Of similar relevance, secreted APP (sA...

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Detalles Bibliográficos
Autores principales: Henriques, A. G., Oliveira, J. M., Gomes, B., Ruivo, R., da Cruz e Silva, E. F., da Cruz e Silva, O. A. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4112052/
https://www.ncbi.nlm.nih.gov/pubmed/24599756
http://dx.doi.org/10.1007/s12031-014-0233-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4112052/
https://www.ncbi.nlm.nih.gov/pubmed/24599756
http://dx.doi.org/10.1007/s12031-014-0233-7

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