Inflammation-induced repression of Foxp3-bound chromatin in regulatory T cells

The transcription factor Foxp3 is indispensable for the ability of regulatory T (Treg) cells to suppress fatal inflammation. Here, we characterized the role of Foxp3 in chromatin remodeling and regulation of gene expression in actively suppressing Treg cells in an inflammatory setting. Although geno...

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Detalles Bibliográficos
Autores principales: Arvey, Aaron, van der Veeken, Joris, Samstein, Robert M., Feng, Yongqiang, Stamatoyannopoulos, John A., Rudensky, Alexander Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4112080/
https://www.ncbi.nlm.nih.gov/pubmed/24728351
http://dx.doi.org/10.1038/ni.2868

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4112080/
https://www.ncbi.nlm.nih.gov/pubmed/24728351
http://dx.doi.org/10.1038/ni.2868

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