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KSHV vCyclin Counters the Senescence/G1 Arrest Response Triggered by NF-κB Hyper-activation
Many oncogenic viruses activate NF-κB as a part of their replicative cycles. We have shown recently that persistent and potentially oncogenic activation of NF-κB by the human T-lymphotropic virus 1 (HTLV-1) oncoprotein Tax immediately triggers a host senescence response mediated by cyclin-dependent...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4112183/ https://www.ncbi.nlm.nih.gov/pubmed/24469036 http://dx.doi.org/10.1038/onc.2013.567 |