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aPKCλ maintains the integrity of the glomerular slit diaphragm through trafficking of nephrin to the cell surface
The slit diaphragm (SD), the specialized intercellular junction between renal glomerular epithelial cells (podocytes), provides a selective-filtration barrier in renal glomeruli. Dysfunction of the SD results in glomerular diseases that are characterized by disappearance of SD components, such as ne...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4112437/ https://www.ncbi.nlm.nih.gov/pubmed/24700503 http://dx.doi.org/10.1093/jb/mvu022 |