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aPKCλ maintains the integrity of the glomerular slit diaphragm through trafficking of nephrin to the cell surface

The slit diaphragm (SD), the specialized intercellular junction between renal glomerular epithelial cells (podocytes), provides a selective-filtration barrier in renal glomeruli. Dysfunction of the SD results in glomerular diseases that are characterized by disappearance of SD components, such as ne...

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Detalles Bibliográficos
Autores principales: Satoh, Daisuke, Hirose, Tomonori, Harita, Yutaka, Daimon, Chikara, Harada, Tomonori, Kurihara, Hidetake, Yamashita, Akio, Ohno, Shigeo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4112437/
https://www.ncbi.nlm.nih.gov/pubmed/24700503
http://dx.doi.org/10.1093/jb/mvu022