Cargando…
aPKCλ maintains the integrity of the glomerular slit diaphragm through trafficking of nephrin to the cell surface
The slit diaphragm (SD), the specialized intercellular junction between renal glomerular epithelial cells (podocytes), provides a selective-filtration barrier in renal glomeruli. Dysfunction of the SD results in glomerular diseases that are characterized by disappearance of SD components, such as ne...
Autores principales: | Satoh, Daisuke, Hirose, Tomonori, Harita, Yutaka, Daimon, Chikara, Harada, Tomonori, Kurihara, Hidetake, Yamashita, Akio, Ohno, Shigeo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4112437/ https://www.ncbi.nlm.nih.gov/pubmed/24700503 http://dx.doi.org/10.1093/jb/mvu022 |
Ejemplares similares
-
An Essential Role of the Universal Polarity Protein, aPKCλ, on the Maintenance of Podocyte Slit Diaphragms
por: Hirose, Tomonori, et al.
Publicado: (2009) -
Loss of aPKCλ in Differentiated Neurons Disrupts the Polarity Complex but Does Not Induce Obvious Neuronal Loss or Disorientation in Mouse Brains
por: Yamanaka, Tomoyuki, et al.
Publicado: (2013) -
A cell polarity protein aPKCλ is required for eye lens formation and growth
por: Sugiyama, Yuki, et al.
Publicado: (2009) -
The KIBRA-aPKC connection: A potential regulator of membrane trafficking and cell polarity
por: Yoshihama, Yohei, et al.
Publicado: (2012) -
Organoids from Nephrotic Disease-Derived iPSCs Identify Impaired NEPHRIN Localization and Slit Diaphragm Formation in Kidney Podocytes
por: Tanigawa, Shunsuke, et al.
Publicado: (2018)