Fatty acid ethyl ester synthase inhibition ameliorates ethanol-induced Ca(2+)-dependent mitochondrial dysfunction and acute pancreatitis

OBJECTIVE: Non-oxidative metabolism of ethanol (NOME) produces fatty acid ethyl esters (FAEEs) via carboxylester lipase (CEL) and other enzyme action implicated in mitochondrial injury and acute pancreatitis (AP). This study investigated the relative importance of oxidative and non-oxidative pathway...

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Detalles Bibliográficos
Autores principales: Huang, Wei, Booth, David M, Cane, Matthew C, Chvanov, Michael, Javed, Muhammad A, Elliott, Victoria L, Armstrong, Jane A, Dingsdale, Hayley, Cash, Nicole, Li, Yan, Greenhalf, William, Mukherjee, Rajarshi, Kaphalia, Bhupendra S, Jaffar, Mohammed, Petersen, Ole H, Tepikin, Alexei V, Sutton, Robert, Criddle, David N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2014
Materias:
Pancreas
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4112447/
https://www.ncbi.nlm.nih.gov/pubmed/24162590
http://dx.doi.org/10.1136/gutjnl-2012-304058

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4112447/
https://www.ncbi.nlm.nih.gov/pubmed/24162590
http://dx.doi.org/10.1136/gutjnl-2012-304058

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