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A sugar phosphatase regulates the methylerythritol phosphate (MEP) pathway in malaria parasites

Isoprenoid biosynthesis through the methylerythritol phosphate (MEP) pathway generates commercially important products and is a target for antimicrobial drug development. MEP pathway regulation is poorly understood in microorganisms. We employ a forward genetics approach to understand MEP pathway re...

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Detalles Bibliográficos
Autores principales: Guggisberg, Ann M., Park, Jooyoung, Edwards, Rachel L., Kelly, Megan L., Hodge, Dana M., Tolia, Niraj H., Odom, Audrey R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4112465/
https://www.ncbi.nlm.nih.gov/pubmed/25058848
http://dx.doi.org/10.1038/ncomms5467