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Modified murine intracranial aneurysm model: aneurysm formation and rupture by elastase and hypertension

INTRODUCTION: Cerebral aneurysms occur in up to 5% of the population. There are several murine models of aneurysms; however, all have limitations and none reproducibly model aneurysm rupture. To fulfill this need, we modified two current rodent aneurysm models to create a murine model which reproduc...

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Detalles Bibliográficos
Autores principales: Hosaka, Koji, Downes, Daniel P, Nowicki, Kamil W, Hoh, Brian L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4112494/
https://www.ncbi.nlm.nih.gov/pubmed/23943816
http://dx.doi.org/10.1136/neurintsurg-2013-010788