Cargando…

A comprehensive search for calcium binding sites critical for TMEM16A calcium-activated chloride channel activity

TMEM16A forms calcium-activated chloride channels (CaCCs) that regulate physiological processes such as the secretions of airway epithelia and exocrine glands, the contraction of smooth muscles, and the excitability of neurons. Notwithstanding intense interest in the mechanism behind TMEM16A-CaCC ca...

Descripción completa

Detalles Bibliográficos
Autores principales: Tien, Jason, Peters, Christian J, Wong, Xiu Ming, Cheng, Tong, Jan, Yuh Nung, Jan, Lily Yeh, Yang, Huanghe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4112547/
https://www.ncbi.nlm.nih.gov/pubmed/24980701
http://dx.doi.org/10.7554/eLife.02772