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Bi-allelic and tri-allelic 5-HTTLPR polymorphisms and triptan non-response in cluster headache

BACKGROUND: Triptans are only effective in terminating cluster headache (CH) attacks in 70-80% of patients. Pharmacogenetic aspects of the serotonin metabolism, specifically variation in the 5-HTTLPR may be involved. METHODS: Genetic association study in a well-defined cohort of 148 CH patients with...

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Detalles Bibliográficos
Autores principales: Schürks, Markus, Frahnow, Antje, Diener, Hans-Christoph, Kurth, Tobias, Rosskopf, Dieter, Grabe, Hans-Jörgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4112603/
https://www.ncbi.nlm.nih.gov/pubmed/25043824
http://dx.doi.org/10.1186/1129-2377-15-46